How it Works

Dogs can be exposed to worms at any time during their life, so it’s important to have confidence your dog's worm protection is working.

Interceptor® Plus (milbemycin oxime/praziquantel) Combines Two Powerful Ingredients

Interceptor Plus has two active ingredients. Milbemycin oxime is an effective way to prevent heartworm disease in dogs, as well as treat and control adult hookworm, roundworm and whipworm infections in dogs. While, praziquantel, the other active ingredient in Interceptor Plus has demonstrated 100% efficacy in controlled studies against 4 species of adult tapeworms: Taenia pisiformis, Echinococcus multilocularis, Echinococcus granulosus and Dipylidium caninum1.

Worms Don’t Stand a Chance

The active ingredients in Interceptor Plus allow you to protect your dog against 5 types of worms.

  • Trusted treatment

    Veterinarians have trusted milbemycin oxime for more than 25 years2 

  • Approved treatment

    Praziquantel has been approved for the treatment of tapeworms in dogs for more than 35 years1 

  • Maximum protection

    Interceptor Plus protects against 2 more types of worms than Heartgard® Plus*

Want to know more about how to give Interceptor Plus to your dog?

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Discover Our FAQs

Find the answers to your questions about Interceptor Plus.


Interceptor Plus prevents heartworm disease and treats and controls adult roundworm, hookworm, whipworm, and tapeworm infections in dogs and puppies 6 weeks or older and 2 pounds or greater.

*Heartgard® Plus (ivermectin/pyrantel) prevents heartworm disease (D. immitis), and treats and controls preexisting hookworm (A. caninum, A. braziliense, U. stenocephala) and roundworm (T. canis, T. leonina) infections.

Important Safety Information

Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Interceptor Plus, dogs should be tested for existing heartworm infections. The safety of Interceptor Plus has not been evaluated in dogs used for breeding or in lactating females. The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel: vomiting, diarrhea, decreased activity, incoordination, weight loss, convulsions, weakness, and salivation. For complete safety information, please see Interceptor Plus product label or ask your veterinarian.

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