Keep Your Pup Protected

Parasites affect their hosts, such as wildlife, people and pets. A proactive approach to protecting your dog is with Trifexis, the #1 prescribed1 combo parasite protection. Learn more about how Trifexis protects your dog from fleas, heartworm disease and three kinds of intestinal parasites.

  • Fleas_1

    Kills fleas on dogs and prevents infestations

  • Worms

    Prevents heartworm disease in dogs

  • Parasites

    Treats and controls hookworm, roundworm and whipworm infections

Give Parasites in Dogs a One-Two Punch

Trifexis combines two powerful, active ingredients that effectively protect your dog against fleas, heartworm disease and three types of dangerous parasites: hookworm, roundworm and whipworm.
Give Parasites in Dogs a One-Two Punch

What is Trifexis?

  • Parasites

    Protects against fleas, heartworm disease, hookworm, roundworm and whipworm.

  • Oral Tablet

    Oral beef-flavored tablet that’s easy to administer

  • Monthly dose

    Convenient once-a-month dosing

  • Month Protection

    Protect all month long with just one tablet

  • Puppy Approved

    Approved for puppies and dogs 8 weeks and older, and who weigh 5 pounds or more

You Might be Interested in…

Want to keep reading? Find more useful resources about effective parasite protection and treatment for your dog.

How it Works

See how Trifexis' mode of action provides effective protection against fleas, heartworm disease, and three harmful intestinal parasites.

Dosing & Administration

Trifexis is available in 5 different strengths according to weight and is safe when used according to the label directions for pup through to adult.

Offers & Promotions

See how you could save money on your Trifexis purchase.


Trifexis prevents heartworm disease. Trifexis kills fleas and prevents flea infestations, and treats and controls adult hookworm, roundworm and whipworm infections in dogs and puppies 8 weeks and older and 5 pounds or more.

Important Safety Information

The use of ivermectin at higher than FDA-approved doses at the same time as Trifexis can result in serious side effects. Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. The most common adverse reactions reported are vomiting, decreased activity, itching, decreased appetite, and diarrhea. To ensure heartworm prevention, observe your dog for one hour after administration. If vomiting occurs within an hour of administration, redose with another full dose. Puppies less than 14 weeks of age may experience a higher rate of vomiting. For complete safety information, please see Trifexis product label or ask your veterinarian.

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Product Overview Module 03-09-002 Trifexis Pack Shot
Trifexis LogoProtect your dog all month long from fleas, heartworm disease and intestinal parasites with Trifexis.

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