Trifexis® (spinosad + milbemycin oxime) Parasite Treatment & Protection

Trifexis is a monthly, beef-flavored tablet that kills fleas and prevents flea infestations, prevents heartworm disease and treats and controls adult hookworm, roundworm and whipworm infections. It is intended for use in dogs and puppies 8 weeks and older, and who weigh 5 pounds or more


Why Switch To Trifexis?

Trifexis kills fleas, prevents heartworm disease and treats and controls intestinal parasites to help your dog stay safe.

Flavoured Chew

Beef-Flavored Chew

Easy-to-administer, once a month beef-flavored tablet.

Complete Protection

All-Round Protection

Trifexis kills fleas, prevents heartworm disease and treats and controls intestinal parasites to help your dog stay safe.

Oral Tablet

Adaptable Dose Range

Trifexis comes in 5 different doses so you can find the one that works best for your puppy or dog, as long as they’re at least 8 weeks old and 5 pounds or greater.

Fast Action

Acts Fast

Trifexis starts killing fleas in just 30 minutes.

Make parasite protection easy with one Trifexis tablet every month for your pup.

Learn More About Trifexis

How Trifexis Works

Trifexis combines two active ingredients that effectively protect your dog against 5 types of dangerous parasites; fleas, heartworm disease, and three types of intestinal parasites.

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Dosing & Administration

Trifexis kills fleas, prevents heartworm disease, and protects against three types of intestinal parasites in dogs with a single monthly oral tablet.

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Never Forget Your Pet’s Medicine Again

Get text or email reminders when it’s time to give your dog each monthly dose, or to refill a Trifexis prescription.

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How it Works

See how Trifexis' mode of action provides effective protection against fleas, heartworm disease, and three harmful intestinal parasites.

Dosing & Administration

Trifexis is available in 5 different strengths according to weight and is safe when used according to the label directions for pup through to adult.

Offers & Promotions

See how you could save money on your Trifexis purchase.

Indications

Trifexis prevents heartworm disease. Trifexis kills fleas and prevents flea infestations, and treats and controls adult hookworm, roundworm and whipworm infections in dogs and puppies 8 weeks and older and 5 pounds or more.

Important Safety Information

The use of ivermectin at higher than FDA-approved doses at the same time as Trifexis can result in serious side effects. Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. The most common adverse reactions reported are vomiting, decreased activity, itching, decreased appetite, and diarrhea. To ensure heartworm prevention, observe your dog for one hour after administration. If vomiting occurs within an hour of administration, redose with another full dose. Puppies less than 14 weeks of age may experience a higher rate of vomiting. For complete safety information, please see Trifexis product label or ask your veterinarian.


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Protect your dog all month long from fleas, heartworm disease and intestinal parasites with Trifexis.

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